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Zestril (Lisinopril)

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Synonyms: Hypernil, Lapril, Lisitec, Acercomp, Inhibril, Linopril, Lisipril, Noperten, Presiten, Prinivil

What is the most important information I should know about Zestril?


•Do not take Zestril if you are pregnant or planning a pregnancy. When used during the second and third trimesters of pregnancy, Zestril can cause injury and even death to the developing fetus. Notify your doctor immediately if you think you might be pregnant.

Zestril may increase the risk of dangerous allergic reactions. Before taking Zestril, tell your doctor if you have ever had an allergic reaction that involved swelling of your lips, face, tongue, or throat or difficulty breathing. Seek emergency medical attention if you develop any of these symptoms while taking Zestril.

•Heavy sweating, vomiting, diarrhea, or other causes of fluid loss may lead to very low blood pressure, dizziness, and fainting during therapy with Zestril. Maintain proper fluid intake to prevent dehydration and related side effects.

What is Zestril?

Zestril is in a class of drugs called angiotensin-converting-enzyme (ACE) inhibitors.

Zestril is used to lower blood pressure, to treat congestive heart failure, and to improve the survival rate after a heart attack.

Zestril may also be used for purposes other than those listed in this medication guide.

Who should not take Zestril?

Zestril may increase the risk of dangerous allergic reactions. Before taking Zestril, tell your doctor if you have ever had an allergic reaction that involved swelling of your lips, face, tongue, or throat or difficulty breathing. Seek emergency medical attention if you develop any of these symptoms while taking Zestril.

•Before taking Zestril, tell your doctor if you

◦have kidney disease;

◦are on a salt-restricted diet or have high levels of potassium in your blood;

◦are taking salt substitutes, potassium supplements (e.g., K-Dur, Klor-Con), or potassium-sparing diuretics such as amiloride (Midamor), triamterene (Dyrenium, Dyazide, Maxzide), or spironolactone (Aldactone); or

◦have diabetes.

•You may not be able to take Zestril, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.

Zestril is in the FDA pregnancy category D. This means that Zestril is known to harm an unborn baby. When used during the second and third trimesters of pregnancy, Zestril can cause injury and even death to the developing fetus.Do not take Zestril if you are pregnant.

•It is not known whether Zestril passes into breast milk, and its effects on a nursing baby are not known. Do not take Zestril without first talking to your doctor if you are breast-feeding a baby.

How should I take Zestril?

•Take Zestril exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

•Take each dose with a full glass of water.

Zestril can be taken with or without food.

•Do not stop taking Zestril without first talking to your doctor. If you stop taking this medication suddenly, your condition could become worse.

•Store Zestril at room temperature away from moisture and heat.

What happens if I miss a dose?

•Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication.

What happens if I overdose?

•Seek emergency medical attention.

•Symptoms of a Zestril overdose include extreme dizziness, weakness, fainting, and fatigue.

What should I avoid while taking Zestril?

•Use caution when driving, operating machinery, or performing other hazardous activities. Zestril may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities and notify your doctor. Also use caution when rising from a sitting or lying position.

•Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking Zestril. Alcohol may further lower blood pressure and increase drowsiness and dizziness when you are taking Zestril.

•Do not use salt substitutes or potassium supplements while taking Zestril except under the supervision of your doctor.

•Heavy sweating, vomiting, diarrhea, or other causes of fluid loss may lead to very low blood pressure, dizziness, and fainting during therapy with Zestril. Maintain proper fluid intake to prevent dehydration and related side effects.

What are the possible side effects of Zestril?

•If you experience any of the following serious side effects, stop taking Zestril and call your doctor immediately or seek emergency medical treatment:

◦an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);

◦difficulty breathing;

◦little or no urine;

◦an irregular heartbeat or changes in your heartbeat;

◦chest pain;

◦severe dizziness or fainting; or

◦signs of an infection including a sore throat or a fever.

•Other, less serious side effects may be more likely to occur. Continue to take Zestril and talk to your doctor if you experience

◦mild dizziness or lightheadedness;

◦headache;

◦unusual fatigue or weakness;

◦dry, tickling cough;

◦muscle cramps;

◦numbness or tingling in the hands, feet, arms, or legs;

◦nausea, vomiting, or diarrhea;

◦a rash; or

◦impotence.

•Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect Zestril?

•Before taking Zestril, tell your doctor if you are taking any of the following drugs:

◦a potassium supplement such as K-Dur, Klor-Con, and others;

◦salt substitutes that contain potassium;

◦any of the diuretics (water pills) triamterene (Dyrenium, Maxzide, Dyazide), spironolactone (Aldactone), or amiloride (Midamor);

◦any other diuretic (water pill) such as hydrochlorothiazide (HCTZ, HydroDiuril, others), furosemide (Lasix), bumetanide (Bumex), indapamide (Lozol), and others;

◦lithium (Lithobid, Eskalith, others); or

◦indomethacin (Indocin).

•You may not be able to take Zestril, or you may require a dosage adjustment or special monitoring during your treatment if you are taking any of the medicines listed above.

•Drugs other than those listed here may also interact with Zestril or affect your condition. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.
 

Zestoretic (Lisinopril + Hydrochlorothiazide)

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Synonyms: Cipril-h, Acercomp, Inhibril, Linopril, Lisipril, Noperten, Presiten, Prinivil, Prinzide, Renacor


What is the most important information I should know about Zestoretic?


Zestoretic is in the FDA pregnancy category D. This means that Zestoretic is known to harm an unborn baby. When used during the second and third trimesters of pregnancy, Zestoretic can cause injury and even death to the developing fetus. Do not take Zestoretic if you are pregnant.

Zestoretic may increase the risk of dangerous allergic reactions. Before taking Zestoretic, tell your doctor if you have ever had an allergic reaction that involved swelling of your lips, face, tongue, or throat or difficulty breathing. Seek emergency medical attention if you develop any of these symptoms while taking Zestoretic.

•Use caution when driving, operating machinery, or performing other hazardous activities. Zestoretic may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities. Also use caution when rising from a sitting or lying position.

What is Zestoretic?

Zestoretic is a thiazide diuretic (water pill). It increases the amount of salt and water you lose in your urine. Zestoretic is used to lower blood pressure and to decrease edema (swelling).

Zestoretic is in a class of drugs called angiotensin-converting-enzyme inhibitors (ACE inhibitors). Zestoretic is used to lower blood pressure and to relieve the symptoms of congestive heart failure, including shortness of breath and swelling of the legs.

Zestoretic is used to treat hypertension (high blood pressure) and to reduce the risk of stroke in patients with hypertension and left ventricular hypertrophy.

Zestoretic may also be used for purposes other than those listed in this medication guide.

Who should not take Zestoretic?

•Do not take Zestoretic if you have an allergy to sulfa-based drugs such as sulfa antibiotics. You may have an allergic reaction to Zestoretic.

Zestoretic is in the FDA pregnancy category D. This means that Zestoretic is known to harm an unborn baby. When used during the second and third trimesters of pregnancy, Zestoretic can cause injury and even death to the developing fetus. Do not take Zestoretic if you are pregnant.

•Before taking Zestoretic, tell your doctor if you

◦have diabetes,

◦have gout,

◦have a collagen vascular disease such as systemic lupus erythematosus or scleroderma,

◦have pancreatitis,

◦have kidney disease,

◦have liver disease,

◦have a blood or bone marrow disease,

◦have any type of heart disease or have had a stroke,

◦are taking salt substitutes, potassium supplements (e.g., K-Dur, Klor-Con), or potassium-sparing diuretics such as amiloride (Midamor), triamterene (Dyrenium, Dyazide, Maxzide), or spironolactone (Aldactone); or

◦are on a salt-restricted diet or have high levels of potassium in your blood.

•You may not be able to take Zestoretic, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.

Zestoretic is in the FDA pregnancy category D. This means that Zestoretic is known to harm an unborn baby. When used during the second and third trimesters of pregnancy, Zestoretic can cause injury and even death to the developing fetus. Do not take Zestoretic if you are pregnant.

Zestoretic passes into breast milk and may harm a nursing infant. It is not known whether Zestoretic passes into breast milk. Do not take this medication without first talking to your doctor if you are breast-feeding a baby.

•If you are over 60 years of age, you may be more likely to experience side effects from Zestoretic. Your doctor may prescribe a lower dose of this medication.

How should I take Zestoretic?

•Take Zestoretic exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

•Take each dose with a full glass of water.

•Do not stop taking this medication without first talking to your doctor. If you stop taking your medication, your condition could become worse.

•Store Zestoretic at room temperature away from moisture and heat.

What happens if I miss a dose?

•Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication.

What happens if I overdose?

•Seek emergency medical attention.

•Symptoms of a Zestoretic overdose include increased urination, nausea, vomiting, diarrhea, dizziness, fainting, weakness, fatigue, and unconsciousness.

What should I avoid while taking Zestoretic?

•Use caution when driving, operating machinery, or performing other hazardous activities. Zestoretic may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities. Also use caution when rising from a sitting or lying position.

•Use alcohol cautiously. Alcohol may further lower blood pressure, causing increased drowsiness and dizziness while you are taking Zestoretic.

•Avoid a diet high in salt. Too much salt may cause your body to retain water and may decrease the effects of Zestoretic. Ask your doctor or nurse about low-salt diet alternatives.

•Do not use salt substitutes or potassium supplements without first talking to your doctor while taking Zestoretic. These products could cause potassium levels in your blood to become dangerously high.

•Avoid prolonged exposure to sunlight. Zestoretic may increase the sensitivity of your skin to sunlight. Use a sunscreen and wear protective clothing when exposure to the sun is unavoidable.

•Heavy sweating, vomiting, diarrhea, or other causes of fluid loss may lead to very low blood pressure, dizziness, and fainting during therapy with Zestoretic. Maintain proper fluid intake to prevent dehydration and related adverse effects.

What are the possible side effects of Zestoretic?

•If you experience any of the following serious side effects, stop taking Zestoretic and seek emergency medical attention:

◦an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);

◦fainting spells;

◦unusual fatigue or abnormal bleeding or bruising;

◦yellow skin or eyes;

◦confusion;

◦fever, chills, or a sore throat;

◦little or no urine;

◦irregular heartbeats; or

◦increased swelling.

•Other, less serious side effects may be more likely to occur. Continue to take Zestoretic and talk to your doctor if you experience

◦dizziness or lightheadedness;

◦headache;

◦fatigue;

◦tingling or numbness in your arms, legs, hands, or feet;

◦excessive urination;

◦muscle weakness or cramps;

◦increased hunger or thirst;

◦nausea, vomiting, diarrhea, constipation, decreased appetite, or changes in taste;

◦sensitivity to sunlight;

◦dry, tickling cough;

◦anxiety or depression; or

◦itching, rash, or increased sweating.

•Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect Zestoretic?

•Before taking Zestoretic, tell your doctor if you are taking any of the medicines listed below:

◦a potassium supplement such as K-Dur, Klor-Con, and others;

◦a salt substitute that contains potassium;

◦another diuretic (water pill) especially triamterene (Dyrenium, Maxzide, Dyazide), spironolactone (Aldactone), or amiloride (Midamor);

◦cholestyramine (Questran) or colestipol (Colestid);

◦a nonsteroidal anti-inflammatory drug (NSAID) such as ibuprofen (Motrin, Advil), ketoprofen (Orudis, Orudis KT, Oruvail), naproxen (Naprosyn, Anaprox, Aleve), diclofenac (Cataflam, Voltaren), etodolac (Lodine), fenoprofen (Nalfon), flurbiprofen (Ansaid), indomethacin (Indocin), ketorolac (Toradol), mefenamic acid (Ponstel), nabumetone (Relafen), oxaprozin (Daypro), piroxicam (Feldene), sulindac (Clinoril), or tolmetin (Tolectin);

◦an oral diabetes medication such as glipizide (Glucotrol), glyburide (Micronase, Glynase, Diabeta), chlorpropamide (Diabinese), tolazamide (Tolinase), tolbutamide (Orinase), and others;

◦tetracycline (Sumycin, others);

◦lithium (Lithane, Lithobid, Eskalith, others);

◦a calcium channel blocker such as amlodipine (Norvasc), diltiazem (Cardizem, Dilacor XR, Tiazac), nifedipine (Adalat, Procardia), verapamil (Calan, Verelan, Isoptin), and others;

◦doxazosin (Cardura), prazosin (Minipress), or terazosin (Hytrin);

◦reserpine, guanadrel (Hylorel), or guanethidine (Ismelin);

◦a nitrate such as nitroglycerin (Nitrostat, Transderm-Nitro, Nitro-Dur, Nitro-Bid, Minitran, others), isosorbide mononitrate (Imdur, ISMO), or isosorbide dinitrate (Isordil, Sorbitrate);

◦a pain reliever such as codeine, morphine (MS Contin, MSIR, Roxanol, others), propoxyphene (Darvocet, Darvon, Wygesic), oxycodone (Percocet, Percodan), meperidine (Demerol), and others;

◦a barbiturate such as phenobarbital (Luminal, Solfoton), amobarbital (Amytal), secobarbital (Seconal), and butabarbital (Butisol); or

◦a steroid medicine such as cortisone (Cortone), dexamethasone (Decadron, Hexadrol), betamethasone (Celestone), hydrocortisone (Cortef, Hydrocortone), prednisone (Orasone, Deltasone), prednisolone (Delta Cortef, Prelone), methylprednisolone (Medrol), and others.

•You may not be able to take Zestoretic, or you may require a dosage adjustment or special monitoring during your treatment if you are taking any of the medicines listed above.

•Drugs other than those listed here may also interact with Zestoretic or affect your condition. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

 

Zebeta (Bisoprolol)

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Synonyms: Biselect, Corbis, Cardicor, Concor, Detensiel, Emcor, Euradal, Isoten, Monocor, Soloc

What is the most important information I should know about Zebeta?


•Do not stop taking Zebeta without first talking to your doctor. Stopping suddenly may make your condition worse.

•If you need to have any type of surgery, you may need to temporarily stop using Zebeta. Be sure the surgeon knows ahead of time that you are using Zebeta.

Zebeta can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

•Avoid drinking alcohol, which could increase drowsiness and dizziness while you are taking Zebeta.

Zebeta is only part of a complete program of treatment for hypertension that may also include diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely if you are being treated for hypertension.

•Hypertension often has no symptoms, so you may not even feel that you have high blood pressure. Continue using this medicine as directed, even if you feel well. You may need to use blood pressure medication for the rest of your life.

What is Zebeta?

Zebeta is in a group of drugs called beta-blockers. Beta-blockers affect the heart and circulation (blood flow through arteries and veins).

Zebeta is used to treat hypertension (high blood pressure).

Zebeta may also be used for purposes other than those listed in this medication guide.

What should I discuss with my healthcare provider before taking Zebeta?

•Before taking Zebeta, tell your doctor if you have:

◦asthma, bronchitis, emphysema;

◦diabetes;

◦low blood pressure;

◦a heart problem such as heart block, sick sinus syndrome, slow heart rate, or congestive heart failure;

◦depression;

◦liver or kidney disease;

◦a thyroid disorder;

◦myasthenia gravis;

◦pheochromocytoma; or

◦problems with circulation (such as Raynaud's syndrome).

•If you have any of these conditions, you may not be able to use Zebeta, or you may need a dosage adjustment or special tests during treatment.

•FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

•It is not known whether Zebeta passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take Zebeta?

•Take Zebeta exactly as it was prescribed for you. Do not take the medication in larger amounts or for longer than recommended by your doctor.

•Take this medication with a full glass of water.

•Take Zebeta at the same time every day.

•Do not skip doses or stop taking Zebeta without first talking to your doctor. Stopping suddenly may make your condition worse.

•To be sure this medication is helping your condition, your blood pressure will need to be checked on a regular basis. It is important that you not miss any scheduled visits to your doctor.

•If you need to have any type of surgery, tell the surgeon that you are using Zebeta. You may need to briefly stop using Zebeta before having surgery.

Zebeta is only part of a complete program of treatment for hypertension that may also include diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely if you are being treated for hypertension.

•Hypertension often has no symptoms, so you may not even feel that you have high blood pressure. Continue using this medicine as directed, even if you feel well. You may need to use blood pressure medication for the rest of your life.

•Store Zebeta at room temperature away from moisture and heat.

What happens if I miss a dose?

•Take the missed dose as soon as you remember. If your next dose is less than 4 hours away, skip the the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

•Seek emergency medical attention if you think you have used too much of this medicine.

•Symptoms of an Zebeta overdose may include uneven heartbeats, shortness of breath, bluish-colored fingernails, dizziness, weakness, fainting, or seizure (convulsions).

What should I avoid while taking Zebeta?

Zebeta can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

•Avoid drinking alcohol, which could increase drowsiness and dizziness while you are taking Zebeta.

What are the possible side effects of Zebeta?

•Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

•Call your doctor at once if you have any of these serious side effects:

◦slow or uneven heartbeats;

◦feeling light-headed, fainting;

◦feeling short of breath, even with mild exertion;

◦swelling of your ankles or feet;

◦nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);

◦depression; or

◦cold feeling in your hands and feet.

•Other less serious side effects are more likely to occur, such as:

◦decreased sex drive, impotence, or difficulty having an orgasm;

◦sleep problems (insomnia);

◦tired feeling; or

◦anxiety, nervousness.

•Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect Zebeta?

•Before taking Zebeta, tell your doctor if you are using:

◦allergy treatments (or if you are undergoing allergy skin-testing);

◦clonidine (Catapres);

◦guanabenz (Wytensin);

◦an MAO inhibitor such as isocarboxazid (Marplan), tranylcypromine (Parnate), phenelzine (Nardil), or selegiline (Eldepryl, Emsam);

◦a diabetes medication such as insulin, glyburide (Diabeta, Micronase, Glynase), glipizide (Glucotrol), chlorpropamide (Diabinese), or metformin (Glucophage);

◦a heart medication such as nifedipine (Procardia, Adalat), reserpine (Serpasil), verapamil (Calan, Verelan, Isoptin), diltiazem (Cartia, Cardizem);

◦medicine for asthma or other breathing disorders, such as albuterol (Ventolin, Proventil), bitolterol (Tornalate), metaproterenol (Alupent), pirbuterol (Maxair), terbutaline (Brethaire, Brethine, Bricanyl), and theophylline (Theo-Dur, Theolair); or

◦cold medicines, stimulant medicines, or diet pills.

•If you are using any of these drugs, you may not be able to take Zebeta, or you may need dosage adjustments or special tests during treatment.

•There may be other drugs not listed that can affect Zebeta. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
 

Vasotec (Enalapril)

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Synonyms: Dilpril, Dilvas, Minipril, Bonuten, Gadopril, Kinfil, Vaseretic

What is the most important information I should know about Vasotec?


•Do not take Vasotec if you are pregnant or could become pregnant during treatment. When used during the second and third trimesters of pregnancy, Vasotec can cause injury and even death to the developing baby. Notify your doctor immediately if you think you might be pregnant.

Vasotec may increase the risk of dangerous allergic reactions. Before taking Vasotec, tell your doctor if you have ever had an allergic reaction that involved swelling of your lips, face, tongue, or throat or difficulty breathing. Seek emergency medical attention if you develop any of these symptoms while taking Vasotec.

•Use caution when driving, operating machinery, or performing other hazardous activities. Vasotec may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities and notify your doctor. Also use caution when rising from a sitting or lying position.

•Heavy sweating, vomiting, diarrhea, or other causes of fluid loss may lead to very low blood pressure, dizziness, and fainting during therapy with Vasotec. Maintain proper fluid intake to prevent dehydration and related adverse effects.

What is Vasotec?

Vasotec is in a class of drugs called angiotensin-converting-enzyme inhibitors (ACE inhibitors).

Vasotec is used to lower blood pressure and to prevent and treat heart failure.

Vasotec may also be used for purposes other than those listed in this medication guide.

What should I discuss with my healthcare provider before taking Vasotec?

Vasotec may increase the risk of dangerous allergic reactions. Before taking Vasotec, tell your doctor if you have ever had an allergic reaction that involved swelling of your lips, face, tongue, or throat or difficulty breathing. Seek emergency medical attention if you develop any of these symptoms while taking Vasotec.

•Before taking Vasotec, tell your doctor if you

◦have kidney disease;

◦have liver disease;

◦are on a salt-restricted diet or have high levels of potassium in your blood;

◦are taking salt substitutes, potassium supplements (e.g., K-Dur, Klor-Con), or potassium-sparing diuretics such as amiloride (Midamor), triamterene (Dyrenium, Dyazide, Maxzide), or spironolactone (Aldactone);

◦have diabetes;

◦have scleroderma or lupus; or

◦have any type of heart disease or have had a stroke.

•You may not be able to take Vasotec, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.

Vasotec is in the FDA pregnancy category D. This means that Vasotec is known to be harmful to an unborn baby. When used during the second and third trimesters of pregnancy, Vasotec can cause injury and even death to the developing baby. Do not take Vasotec if you are pregnant or could become pregnant during treatment.

•It is not known whether Vasotec passes into breast milk. Do not use Vasotec without first talking to your doctor if you are breast-feeding a baby.

How should I take Vasotec?

•Take Vasotec exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

•Take each dose with a full glass of water.

•Do not stop taking Vasotec without first talking to your doctor. If you stop taking this medication suddenly, your condition could become worse.

•Store Vasotec at room temperature away from moisture and heat.

What happens if I miss a dose?

•Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication.

What happens if I overdose?

•Seek emergency medical attention if an overdose is suspected.

•Symptoms of an Vasotec overdose include extreme dizziness, weakness, fainting, and fatigue.

What should I avoid while taking Vasotec?

•Use caution when driving, operating machinery, or performing other hazardous activities. Vasotec may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities and notify your doctor. Also use caution when rising from a sitting or lying position.

•Use alcohol cautiously. Alcohol may further lower blood pressure and increase drowsiness and dizziness while you are taking Vasotec.

•Do not use salt substitutes or potassium supplements while taking Vasotec except under the direction of your doctor.

•Heavy sweating, vomiting, diarrhea, or other causes of fluid loss may lead to very low blood pressure, dizziness, and fainting during therapy with Vasotec. Maintain proper fluid intake to prevent dehydration and related side effects.

What are the possible side effects of Vasotec?

•If you experience any of the following serious side effects, stop taking Vasotec and call your doctor immediately or seek emergency medical treatment:

◦an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);

◦difficulty breathing;

◦little or no urine;

◦chest pain;

◦severe dizziness or fainting; or

◦signs of an infection including a sore throat or a fever.

•Other, less serious side effects may be more likely to occur. Continue to take Vasotec and talk to your doctor if you experience

◦mild dizziness or lightheadedness;

◦headache;

◦dry, tickling cough;

◦numbness or tingling in the hands, feet, arms, or legs;

◦nausea or diarrhea;

◦weakness or fatigue; or

◦a rash.

•Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect Vasotec?

•Before taking Vasotec, tell your doctor if you are taking any of the following drugs:

◦a potassium supplement such as K-Dur, Klor-Con, and others;

◦salt substitutes that contain potassium;

◦any of the diuretics (water pills) triamterene (Dyrenium, Maxzide, Dyazide), spironolactone (Aldactone), or amiloride (Midamor);

◦any other diuretic (water pill) such as hydrochlorothiazide (HCTZ, HydroDiuril, others), furosemide (Lasix), bumetanide (Bumex), indapamide (Lozol), and others; or

◦lithium (Lithobid, Eskalith, others).

•You may not be able to take Vasotec, or you may require a dosage adjustment or special monitoring during your treatment if you are taking any of the medicines listed above.

•Drugs other than those listed here may also interact with Vasotec or affect your condition. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.
 

Valsartan

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Synonyms: Valsarran, Valzaar

Valsartan is used for:


Treating high blood pressure alone or with other medicines. It is used to treat heart failure. It is used in certain patients to decrease the risk of death after a heart attack. It may also be used for other conditions as determined by your doctor.



Valsartan is an angiotensin II receptor blocker (ARB). It works by relaxing the blood vessels. This helps to lower blood pressure.



Do NOT use Valsartan if:

•you are allergic to any ingredient in Valsartan

•you are pregnant

•the patient is a child with severe kidney problems

Contact your doctor or health care provider right away if any of these apply to you.



Before using Valsartan:

Some medical conditions may interact with Valsartan. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:



•if you are pregnant, planning to become pregnant, or are breast-feeding

•if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

•if you have allergies to medicines, foods, or other substances

•if you are able to become pregnant

•if you have a history of angioedema (eg, swelling of the hands, face, lips, eyes, throat, or tongue; difficulty swallowing or breathing; hoarseness), including angioedema caused by treatment with an angiotensin-converting enzyme (ACE) inhibitor (eg, lisinopril)

•if you have a history of heart problems (eg, heart failure), blood vessel problems, blood flow problems, liver or kidney problems, gallbladder problems, or diabetes

•if you have a history of stroke or recent heart attack

•if you are dehydrated or have low blood volume

•if you have electrolyte problems (eg, high blood potassium levels, low blood sodium levels) or are on a low-salt (sodium) diet

•if you are on dialysis or are scheduled to have major surgery

•if you take another medicine for blood pressure or heart problems

Some MEDICINES MAY INTERACT with Valsartan. Tell your health care provider if you are taking any other medicines, especially any of the following:



•Diuretics (eg, furosemide, hydrochlorothiazide) because the risk of low blood pressure may be increased

•Potassium-sparing diuretics (eg, spironolactone, triamterene) or potassium supplements because the risk of high blood potassium levels may be increased

•Nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, celecoxib, ibuprofen, indomethacin) because they may decrease Valsartan's effectiveness

•Lithium because the risk of its side effects may be increased by Valsartan

This may not be a complete list of all interactions that may occur. Ask your health care provider if Valsartan may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.



How to use Valsartan:

Use Valsartan as directed by your doctor. Check the label on the medicine for exact dosing instructions.



•An extra patient leaflet is available with Valsartan. Talk to your pharmacist if you have questions about this information.

•Take Valsartan by mouth with or without food.

•Take Valsartan on a regular schedule to get the most benefit from it. Taking Valsartan at the same time each day will help you remember to take it.

•Continue to take Valsartan even if you feel well. Do not miss any doses.

•If you miss a dose of Valsartan, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Valsartan.



Important safety information:

Valsartan may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Valsartan with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

Valsartan may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.

Valsartan may cause a serious side effect called angioedema. Contact your doctor at once if you develop swelling of the hands, face, lips, eyes, throat, or tongue; difficulty swallowing or breathing; or hoarseness.

Valsartan may not work as well in black patients. Discuss any questions or concerns with your doctor.

•Dehydration, excessive sweating, vomiting, or diarrhea may increase the risk of low blood pressure. Contact your health care provider at once if any of these occur.

•Check with your doctor before you use a salt substitute or a product that has potassium in it.

•Tell your doctor or dentist that you take Valsartan before you receive any medical or dental care, emergency care, or surgery.

•Patients who take medicine for high blood pressure often feel tired or run down for a few weeks after starting treatment. Be sure to take your medicine even if you may not feel “normal”. Tell your doctor if you develop any new symptoms.

•If you have high blood pressure, do not use nonprescription products that contain stimulants. These products may include diet pills or cold medicines. Contact your doctor if you have any questions or concerns.

•Lab tests, including blood pressure, blood electrolyte levels, and heart, kidney, or liver function, may be performed while you use Valsartan. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.

Valsartan should not be used in CHILDREN younger than 6 years old; safety and effectiveness in these children have not been confirmed.

pregnancy and BREAST-FEEDING: Valsartan may cause birth defects or fetal death if you take it while you are pregnant. If you think you may be pregnant, contact your doctor right away. It is not known if Valsartan is found in breast milk. If you are or will be breast-feeding while you use Valsartan, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Valsartan:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



•Diarrhea; dizziness; headache; joint or back pain; mild flu-like symptoms; stomach pain; tiredness.

Seek medical attention right away if any of these SEVERE side effects occur:



•Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred vision; change in the amount of urine produced; chest pain; dark urine; difficulty swallowing; fast, slow, or irregular heartbeat; fainting; muscle pain or cramps; severe or persistent stomach pain (with or without nausea or vomiting); symptoms of low blood pressure (eg, fainting, lightheadedness, severe dizziness); unusual bruising or bleeding; yellowing of the eyes or skin.
 

Tritace (Ramipril)

|

Synonyms: Acovil, Altace, Carasel, Cardace, Delix, Hytren, Lostapres, Pramace, Ramace, Ramipress

What is the most important information I should know about Tritace?


Do not use this medication without telling your doctor if you are pregnant or planning a pregnancy. Tritace could cause birth defects in the baby if you take the medication during pregnancy. Use an effective form of birth control. Stop using this medication and tell your doctor right away if you become pregnant during treatment. Tritace can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.



Vomiting, diarrhea, or heavy sweating can cause you to become dehydrated. This can lead to very low blood pressure, electrolyte disorders, or kidney failure while you are taking Tritace. Drink 6 to 8 full glasses of water daily while you are taking this medication.



What is Tritace?

Tritace is in a group of drugs called ACE inhibitors. ACE stands for angiotensin converting enzyme.



Tritace is used to treat high blood pressure (hypertension), heart failure, and to improve survival after a heart attack.



Tritace may also be used for purposes other than those listed in this medication guide.



What should I discuss with my healthcare provider before taking Tritace?

Do not use this medication if you are allergic to Tritace or to any other ACE inhibitor, such as benazopril (Lotensin), captopril (Capoten), fosinopril (Monopril), enalapril (Vasotec), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), or trandolapril (Mavik).



Before using Tritace, tell your doctor if you are allergic to any drugs, or if you have:



•kidney disease (or if you are on dialysis);

•liver disease;

•heart disease or congestive heart failure;

•diabetes; or

•a connective tissue disease such as Marfan syndrome, Sjogrens syndrome, lupus, scleroderma, or rheumatoid arthritis.

If you have any of these conditions, you may not be able to use Tritace, or you may need a dosage adjustment or special tests during treatment.



FDA pregnancy category D. Do not use this medication without telling your doctor if you are pregnant or planning a pregnancy. Tritace could cause birth defects in the baby if you take the medication during pregnancy. Use an effective form of birth control. Stop using this medication and tell your doctor right away if you become pregnant during treatment. Tritace can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.



How should I take Tritace?

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.



Your doctor may occasionally change your dose to make sure you get the best results from this medication.



Take each dose with a full glass of water.



Tritace can be taken with or without food.



Vomiting, diarrhea, or heavy sweating can cause you to become dehydrated. This can lead to very low blood pressure, electrolyte disorders, or kidney failure while you are taking Tritace. Drink 6 to 8 full glasses of water daily while you are taking this medication.



To be sure this medication is helping your condition, your blood pressure will need to be checked on a regular basis. Your kidney or liver function may also need to be tested. Do not miss any scheduled visits to your doctor.



If you need to have any type of surgery, tell the surgeon ahead of time that you are taking Tritace. You may need to stop using the medicine for a short time.



If you are being treated for high blood pressure, keep using this medication even if you feel fine. High blood pressure often has no symptoms.



Store Tritace at room temperature away from moisture and heat.



What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.



What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine. Symptoms of a Tritace overdose may include feeling extremely dizzy or light-headed, or fainting.



What should I avoid while taking Tritace?

Tritace can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol. It can further lower your blood pressure and may increase some of the side effects of Tritace. Do not use salt substitutes or potassium supplements while taking Tritace, unless your doctor has told you to.



What are the possible side effects of Tritace?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; severe stomach pain; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:



•feeling light-headed, fainting;

•urinating more or less than usual, or not at all;

•fever, chills, body aches, flu symptoms;

•pale skin, easy bruising or bleeding;

•tired feeling, muscle weakness, and pounding or uneven heartbeats;

•chest pain; or

•swelling, rapid weight gain.

Less serious side effects may be more likely to occur, such as:



•cough;

•dizziness, drowsiness, headache;

•sleep problems (insomnia);

•decreased sex drive, impotence, or difficulty having an orgasm;

•nausea, vomiting; or

•mild skin itching or rash.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.



What other drugs will affect Tritace?

Before taking Tritace, tell your doctor if you are taking any of the following drugs:



•lithium (Lithobid, Eskalith);

•a potassium supplement such as K-Dur, Klor-Con;

•salt substitutes that contain potassium;

•aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs) such as ibuprofen (Motrin, Advil), diclofenac (Voltaren), diflunisal (Dolobid), etodolac (Lodine), flurbiprofen (Ansaid), indomethacin (Indocin), ketoprofen (Orudis), ketorolac (Toradol), mefenamic acid (Ponstel), meloxicam (Mobic), nabumetone (Relafen), naproxen (Aleve, Naprosyn), piroxicam (Feldene); or

•a diuretic (water pill) such as amiloride (Midamor), bumetanide (Bumex), chlorthalidone (Hygroton, Thalitone), ethacrynic acid (Edecrin), furosemide (Lasix), hydrochlorothiazide (HCTZ, HydroDiuril), indapamide (Lozol), metolazone (Mykrox, Zarxolyn), spironolactone (Aldactone), triamterene (Dyrenium, Maxzide, Dyazide), torsemide (Demadex).

If you are using any of these drugs, you may not be able to use Tritace or you may need dosage adjustments or special tests during treatment.



There may be other drugs not listed that can affect Tritace. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Toprol XR (Metroprolol XR)

|

Synonyms: Beloc, Betaloc, Lopresor, Metolar, Prelis, Seloken, Selopral
What is the most important information I should know about Toprol?


Do not stop taking Toprol without first talking to your doctor. Stopping suddenly may make your condition worse.



If you need to have any type of surgery, you may need to temporarily stop using Toprol. Be sure the surgeon knows ahead of time that you are using Toprol.



Toprol can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol, which could increase drowsiness and dizziness while you are taking Toprol.



Toprol is only part of a complete program of treatment for hypertension that may also include diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely if you are being treated for hypertension.



Hypertension often has no symptoms, so you may not even feel that you have high blood pressure. Continue using this medicine as directed, even if you feel well. You may need to use blood pressure medication for the rest of your life.



What is Toprol?

Toprol is in a group of drugs called beta-blockers. Beta-blockers affect the heart and circulation (blood flow through arteries and veins).



Toprol is used to treat angina (chest pain) and hypertension (high blood pressure). It is also used to treat or prevent heart attack.



Toprol may also be used for purposes other than those listed in this medication guide.



What should I discuss with my healthcare provider before taking Toprol?

Do not use this medication if you are allergic to Toprol, or if you have:



•a heart problem such as heart block, sick sinus syndrome, or slow heart rate;

•pheochromocytoma; or

•problems with circulation (such as Raynauds syndrome).

Before taking Toprol, tell your doctor if you have:



•congestive heart failure;

•asthma, bronchitis, emphysema;

•diabetes;

•low blood pressure;

•depression;

•liver or kidney disease;

•a thyroid disorder; or

•myasthenia gravis.

If you have any of these conditions, you may not be able to use Toprol, or you may need a dosage adjustment or special tests during treatment.



FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Toprol can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.



How should I take Toprol?

Take Toprol exactly as it was prescribed for you. Do not take the medication in larger amounts or for longer than recommended by your doctor.



Take this medication with a full glass of water.



Take Toprol at the same time every day.



A Toprol XL tablet can be divided in half if your doctor has told you to do so. The half tablet should be swallowed whole, without chewing or crushing. Chewing or crushing the pill could cause too much of the drug to be released at one time. Do not skip doses or stop taking Toprol without first talking to your doctor. Stopping suddenly may make your condition worse.



To be sure this medication is helping your condition, your blood pressure will need to be checked on a regular basis. It is important that you not miss any scheduled visits to your doctor.



If you need to have any type of surgery, tell the surgeon that you are using Toprol. You may need to briefly stop using Toprol before having surgery.



Toprol is only part of a complete program of treatment for hypertension that may also include diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely if you are being treated for hypertension.



Hypertension often has no symptoms, so you may not even feel that you have high blood pressure. Continue using this medicine as directed, even if you feel well. You may need to use blood pressure medication for the rest of your life.



Store Toprol at room temperature away from moisture and heat.



What happens if I miss a dose?

Take the missed dose as soon as you remember. If your next dose is less than 4 hours away, skip the the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.



What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.



Symptoms of an Toprol overdose may include uneven heartbeats, shortness of breath, bluish-colored fingernails, dizziness, weakness, fainting, or seizure (convulsions).



What should I avoid while taking Toprol?

Toprol can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol, which could increase drowsiness and dizziness while you are taking Toprol.



What are the possible side effects of Toprol?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:



•slow or uneven heartbeats;

•feeling light-headed, fainting;

•feeling short of breath, even with mild exertion;

•swelling of your ankles or feet;

•nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);

•depression; or

•cold feeling in your hands and feet.

Other less serious side effects are more likely to occur, such as:



•vomiting;

•decreased sex drive, impotence, or difficulty having an orgasm;

•sleep problems (insomnia);

•tired feeling; or

•anxiety, nervousness.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.



What other drugs will affect Toprol?

Before taking Toprol, tell your doctor if you are using:



•digoxin (digitalis, Lanoxin);

•clonidine (Catapres);

•ritonavir (Norvir);

•terbinafine (Lamisil);

•anti-malaria medications such as chloroquine (Aralen) or hydroxychloroquine (Plaquenil, Quineprox);

•medicine to treat depression or mental illness, such as bupropion (Wellbutrin, Zyban), fluoxetine (Prozac, Sarafem), paroxetine (Paxil), thioridazine (Mellaril), and others;

•an MAO inhibitor such as isocarboxazid (Marplan), tranylcypromine (Parnate), phenelzine (Nardil), or selegiline (Eldepryl, Emsam);

•a diabetes medication such as insulin, glyburide (Diabeta, Micronase, Glynase), glipizide (Glucotrol), chlorpropamide (Diabinese), or metformin (Glucophage);

•a heart medication such as nifedipine (Procardia, Adalat), quinidine (Quinaglute, Quinidex), propafenone (Rythmol), reserpine (Serpasil), verapamil (Calan, Verelan, Isoptin), diltiazem (Cartia, Cardizem);

•medicine for asthma or other breathing disorders, such as albuterol (Ventolin, Proventil), bitolterol (Tornalate), metaproterenol (Alupent), pirbuterol (Maxair), terbutaline (Brethaire, Brethine, Bricanyl), and theophylline (Theo-Dur, Theolair);

•a diuretic (water pill) such as amiloride (Midamor, Moduretic), chlorthalidone (Hygroton, Thalitone), furosemide (Lasix), hydrochlorothiazide (HCTZ, HydroDiuril, Hyzaar, Lopressor, Vasoretic, Zestoretic), spironolactone (Aldactazide, Aldactone), triamterene (Dyrenium, Maxzide, Dyazide), torsemide (Demadex), and others; or

•cold medicines, stimulant medicines, or diet pills.

If you are using any of these drugs, you may not be able to take Toprol, or you may need dosage adjustments or special tests during treatment.



There may be other drugs not listed that can affect Toprol. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

What is the most important information I should know about Toprol?


Do not stop taking Toprol without first talking to your doctor. Stopping suddenly may make your condition worse.



If you need to have any type of surgery, you may need to temporarily stop using Toprol. Be sure the surgeon knows ahead of time that you are using Toprol.



Toprol can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol, which could increase drowsiness and dizziness while you are taking Toprol.



Toprol is only part of a complete program of treatment for hypertension that may also include diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely if you are being treated for hypertension.



Hypertension often has no symptoms, so you may not even feel that you have high blood pressure. Continue using this medicine as directed, even if you feel well. You may need to use blood pressure medication for the rest of your life.



What is Toprol?

Toprol is in a group of drugs called beta-blockers. Beta-blockers affect the heart and circulation (blood flow through arteries and veins).



Toprol is used to treat angina (chest pain) and hypertension (high blood pressure). It is also used to treat or prevent heart attack.



Toprol may also be used for purposes other than those listed in this medication guide.



What should I discuss with my healthcare provider before taking Toprol?

Do not use this medication if you are allergic to Toprol, or if you have:



•a heart problem such as heart block, sick sinus syndrome, or slow heart rate;

•pheochromocytoma; or

•problems with circulation (such as Raynauds syndrome).

Before taking Toprol, tell your doctor if you have:



•congestive heart failure;

•asthma, bronchitis, emphysema;

•diabetes;

•low blood pressure;

•depression;

•liver or kidney disease;

•a thyroid disorder; or

•myasthenia gravis.

If you have any of these conditions, you may not be able to use Toprol, or you may need a dosage adjustment or special tests during treatment.



FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Toprol can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.



How should I take Toprol?

Take Toprol exactly as it was prescribed for you. Do not take the medication in larger amounts or for longer than recommended by your doctor.



Take this medication with a full glass of water.



Take Toprol at the same time every day.



A Toprol XL tablet can be divided in half if your doctor has told you to do so. The half tablet should be swallowed whole, without chewing or crushing. Chewing or crushing the pill could cause too much of the drug to be released at one time. Do not skip doses or stop taking Toprol without first talking to your doctor. Stopping suddenly may make your condition worse.



To be sure this medication is helping your condition, your blood pressure will need to be checked on a regular basis. It is important that you not miss any scheduled visits to your doctor.



If you need to have any type of surgery, tell the surgeon that you are using Toprol. You may need to briefly stop using Toprol before having surgery.



Toprol is only part of a complete program of treatment for hypertension that may also include diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely if you are being treated for hypertension.



Hypertension often has no symptoms, so you may not even feel that you have high blood pressure. Continue using this medicine as directed, even if you feel well. You may need to use blood pressure medication for the rest of your life.



Store Toprol at room temperature away from moisture and heat.



What happens if I miss a dose?

Take the missed dose as soon as you remember. If your next dose is less than 4 hours away, skip the the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.



What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.



Symptoms of an Toprol overdose may include uneven heartbeats, shortness of breath, bluish-colored fingernails, dizziness, weakness, fainting, or seizure (convulsions).



What should I avoid while taking Toprol?

Toprol can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol, which could increase drowsiness and dizziness while you are taking Toprol.



What are the possible side effects of Toprol?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:



•slow or uneven heartbeats;

•feeling light-headed, fainting;

•feeling short of breath, even with mild exertion;

•swelling of your ankles or feet;

•nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);

•depression; or

•cold feeling in your hands and feet.

Other less serious side effects are more likely to occur, such as:



•vomiting;

•decreased sex drive, impotence, or difficulty having an orgasm;

•sleep problems (insomnia);

•tired feeling; or

•anxiety, nervousness.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.



What other drugs will affect Toprol?

Before taking Toprol, tell your doctor if you are using:



•digoxin (digitalis, Lanoxin);

•clonidine (Catapres);

•ritonavir (Norvir);

•terbinafine (Lamisil);

•anti-malaria medications such as chloroquine (Aralen) or hydroxychloroquine (Plaquenil, Quineprox);

•medicine to treat depression or mental illness, such as bupropion (Wellbutrin, Zyban), fluoxetine (Prozac, Sarafem), paroxetine (Paxil), thioridazine (Mellaril), and others;

•an MAO inhibitor such as isocarboxazid (Marplan), tranylcypromine (Parnate), phenelzine (Nardil), or selegiline (Eldepryl, Emsam);

•a diabetes medication such as insulin, glyburide (Diabeta, Micronase, Glynase), glipizide (Glucotrol), chlorpropamide (Diabinese), or metformin (Glucophage);

•a heart medication such as nifedipine (Procardia, Adalat), quinidine (Quinaglute, Quinidex), propafenone (Rythmol), reserpine (Serpasil), verapamil (Calan, Verelan, Isoptin), diltiazem (Cartia, Cardizem);

•medicine for asthma or other breathing disorders, such as albuterol (Ventolin, Proventil), bitolterol (Tornalate), metaproterenol (Alupent), pirbuterol (Maxair), terbutaline (Brethaire, Brethine, Bricanyl), and theophylline (Theo-Dur, Theolair);

•a diuretic (water pill) such as amiloride (Midamor, Moduretic), chlorthalidone (Hygroton, Thalitone), furosemide (Lasix), hydrochlorothiazide (HCTZ, HydroDiuril, Hyzaar, Lopressor, Vasoretic, Zestoretic), spironolactone (Aldactazide, Aldactone), triamterene (Dyrenium, Maxzide, Dyazide), torsemide (Demadex), and others; or

•cold medicines, stimulant medicines, or diet pills.

If you are using any of these drugs, you may not be able to take Toprol, or you may need dosage adjustments or special tests during treatment.



There may be other drugs not listed that can affect Toprol. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Toprol XL (Metroprolol XL)

|

Synonyms: Beloc, Betaloc, Lopresor, Metolar, Prelis, Seloken, Selopral

What is the most important information I should know about toprol?


Do not stop taking Toprol without first talking to your doctor. Stopping suddenly may make your condition worse.



If you need to have any type of surgery, you may need to temporarily stop using toprol. Be sure the surgeon knows ahead of time that you are using toprol.



Toprol can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol, which could increase drowsiness and dizziness while you are taking toprol.



Toprol is only part of a complete program of treatment for hypertension that may also include diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely if you are being treated for hypertension.



Hypertension often has no symptoms, so you may not even feel that you have high blood pressure. Continue using this medicine as directed, even if you feel well. You may need to use blood pressure medication for the rest of your life.



What is toprol?

Toprol is in a group of drugs called beta-blockers. Beta-blockers affect the heart and circulation (blood flow through arteries and veins).



Toprol is used to treat angina (chest pain) and hypertension (high blood pressure). It is also used to treat or prevent heart attack.



Toprol may also be used for purposes other than those listed in this medication guide.



What should I discuss with my healthcare provider before taking toprol?

Do not use this medication if you are allergic to toprol, or if you have:



•a heart problem such as heart block, sick sinus syndrome, or slow heart rate;

•pheochromocytoma; or

•problems with circulation (such as Raynauds syndrome).

Before taking toprol, tell your doctor if you have:



•congestive heart failure;

•asthma, bronchitis, emphysema;

•diabetes;

•low blood pressure;

•depression;

•liver or kidney disease;

•a thyroid disorder; or

•myasthenia gravis.

If you have any of these conditions, you may not be able to use toprol, or you may need a dosage adjustment or special tests during treatment.



FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Toprol can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.



How should I take toprol?

Take Toprol exactly as it was prescribed for you. Do not take the medication in larger amounts or for longer than recommended by your doctor.



Take this medication with a full glass of water.



Take Toprol at the same time every day.



A Toprol XL tablet can be divided in half if your doctor has told you to do so. The half tablet should be swallowed whole, without chewing or crushing. Chewing or crushing the pill could cause too much of the drug to be released at one time. Do not skip doses or stop taking Toprol without first talking to your doctor. Stopping suddenly may make your condition worse.



To be sure this medication is helping your condition, your blood pressure will need to be checked on a regular basis. It is important that you not miss any scheduled visits to your doctor.



If you need to have any type of surgery, tell the surgeon that you are using toprol. You may need to briefly stop using Toprol before having surgery.



Toprol is only part of a complete program of treatment for hypertension that may also include diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely if you are being treated for hypertension.



Hypertension often has no symptoms, so you may not even feel that you have high blood pressure. Continue using this medicine as directed, even if you feel well. You may need to use blood pressure medication for the rest of your life.



Store Toprol at room temperature away from moisture and heat.



What happens if I miss a dose?

Take the missed dose as soon as you remember. If your next dose is less than 4 hours away, skip the the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.



What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.



Symptoms of an Toprol overdose may include uneven heartbeats, shortness of breath, bluish-colored fingernails, dizziness, weakness, fainting, or seizure (convulsions).



What should I avoid while taking toprol?

Toprol can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol, which could increase drowsiness and dizziness while you are taking toprol.



What are the possible side effects of toprol?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:



•slow or uneven heartbeats;

•feeling light-headed, fainting;

•feeling short of breath, even with mild exertion;

•swelling of your ankles or feet;

•nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);

•depression; or

•cold feeling in your hands and feet.

Other less serious side effects are more likely to occur, such as:



•vomiting;

•decreased sex drive, impotence, or difficulty having an orgasm;

•sleep problems (insomnia);

•tired feeling; or

•anxiety, nervousness.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.



What other drugs will affect toprol?

Before taking toprol, tell your doctor if you are using:



•digoxin (digitalis, Lanoxin);

•clonidine (Catapres);

•ritonavir (Norvir);

•terbinafine (Lamisil);

•anti-malaria medications such as chloroquine (Aralen) or hydroxychloroquine (Plaquenil, Quineprox);

•medicine to treat depression or mental illness, such as bupropion (Wellbutrin, Zyban), fluoxetine (Prozac, Sarafem), paroxetine (Paxil), thioridazine (Mellaril), and others;

•an MAO inhibitor such as isocarboxazid (Marplan), tranylcypromine (Parnate), phenelzine (Nardil), or selegiline (Eldepryl, Emsam);

•a diabetes medication such as insulin, glyburide (Diabeta, Micronase, Glynase), glipizide (Glucotrol), chlorpropamide (Diabinese), or metformin (Glucophage);

•a heart medication such as nifedipine (Procardia, Adalat), quinidine (Quinaglute, Quinidex), propafenone (Rythmol), reserpine (Serpasil), verapamil (Calan, Verelan, Isoptin), diltiazem (Cartia, Cardizem);

•medicine for asthma or other breathing disorders, such as albuterol (Ventolin, Proventil), bitolterol (Tornalate), metaproterenol (Alupent), pirbuterol (Maxair), terbutaline (Brethaire, Brethine, Bricanyl), and theophylline (Theo-Dur, Theolair);

•a diuretic (water pill) such as amiloride (Midamor, Moduretic), chlorthalidone (Hygroton, Thalitone), furosemide (Lasix), hydrochlorothiazide (HCTZ, HydroDiuril, Hyzaar, Lopressor, Vasoretic, Zestoretic), spironolactone (Aldactazide, Aldactone), triamterene (Dyrenium, Maxzide, Dyazide), torsemide (Demadex), and others; or

•cold medicines, stimulant medicines, or diet pills.

If you are using any of these drugs, you may not be able to take toprol, or you may need dosage adjustments or special tests during treatment.



There may be other drugs not listed that can affect toprol. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.